Microsoft's April 2026 Patch Tuesday addresses 163 CVEs across 17 product families, including 8 Critical vulnerabilities and one actively exploited zero-day (CVE-2026-32201 in SharePoint). Organizations should prioritize patching the exploited SharePoint flaw, the publicly disclosed Defender bug (CVE-2026-33825), and a highly critical 9.8 CVSS RCE in Windows IKE (CVE-2026-33824).